HIV1 tat HxB2 protein (HRP) (65-017002)
Purified recombinant HIV1 tat HxB2 (HRP)
Overview
Overview
| Synonyms | HIV 1 tat protein, Histone acetyltransferase HTATIP protein, HIV-1 tat protein, cPLA protein, HIV-1 tat protein, HIV 1 tat, Tat protein, 60 kDa Tat interactive protein, HIV1 tat, HTATIP1 protein, TIP60 protein, Human tat interactive protein mRNA complete cds protein, HIV 1 Tat interacting protein protein, PLIP protein, HIV 1 Tat interacting protein 60kDa protein, ESA1 protein, HIV 1 tat protein, TIP protein, EC 2.3.1.48 protein, Tat interactive protein (60kD) protein, HIV-1 tat, Transactivating regulatory protein protein |
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| Species | Viral |
| Protein Type | Recombinant |
| Applications | ELISA, WB |
Specifications
| Expression System | E.coli |
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| Grade & Purity | > 90% pure |
| Tag/Conjugate | HRP |
Storage & Safety
| Storage | Store lyophilized product at 2-8 deg C short term, following reconstitution, aliquot and store at -70 deg C or lower. Avoid repeated freeze/thaw cycles |
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General Information
| Biological Significance | Tat vastly increases the level of transcription of the HIV dsRNA. Before Tat is present, a small number of RNA transcripts will be made, which allow the Tat protein to be produced. Tat then binds to cellular factors and mediates their phosphorylation, resulting in increased transcription of all HIV genes, providing a positive feedback cycle. This in turn allows HIV to have an explosive response once a threshold amount of Tat is produced, a useful tool for defeating the body's response. |
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