HSP47 protein (His tag) (80R-1100)

Purified recombinant Human HSP47 protein

Synonyms Hsp 47 protein, J6 protein, SERPINH1 protein, Serpin peptidase inhibitor clade H member 1., Arsenic transactivated protein 3 protein, RA A47 protein, HSP 47 protein, HSP-47, Serpin H1 protein, Colligin 2 protein, AsTP3 protein, PIG 14 protein, HSP 47, Colligin 1 protein, RA-A47 protein, PPROM protein, Rheumatoid arthritis related protein RA A47 protein, gp46 protein, Serine or cysteine proteinase inhibitor clade H member 1 protein, Collagen binding protein 1 protein, Serpin H1 protein, Proliferation inducing gene 14 protein, Serine or cysteine proteinase inhibitor clade H member 2 protein, AsTP 3 protein, CBP 1 protein, HGNC 1547 protein, CBP1 protein, Rheumatoid arthritis protein A 47 protein, 47 kDa heat shock protein precursor protein, 47 kDa heat shock protein protein, Heat shock protein 47 protein, HSP47, PIG14 protein, Collogin protein, Proliferation inducing gene 14 protein protein, Collagen binding protein protein, Heme oxygenase 1 protein, Collagen binding protein 2 protein, Colligen protein, CBP2 protein, HSP-47 protein, HSP47 protein, CBP 2 protein, Collagen-binding protein protein, SERPINH2 protein
Species Human
Protein Type Recombinant
Applications SDS-PAGE

Specifications

Residues 18-418 amino acids: MRGSHHHHHH GMASMTGGQQ MGRDLYDDDD KDRWGSHMAA EVKKPAAAAA PGTAEKLSPK AATLAERSAG LAFSLYQAMA KDQAVENILV SPVVVASSLG LVSLGGKATT ASQAKAVLSA EQLRDEEVHA GLGELLRSLS NSTARNVTWK LGSRLYGPSS VSFADDFVRS SKQHYNCEHS KINFRDKRSA LQSINEWAAQ TTDGKLPEVT KDVERTDGAL LVNAMFFKPH WDEKFHHKMV DNRGFMVTRS YTVGVMMMHR TGLYNYYDDE KEKLQIVEMP LAHKLSSLII LMPHHVEPLE RLEKLLTKEQ LKIWMGKMQK KAVAISLPKG VVEVTHDLQK HLAGLGLTEA IDKNKADLSR MSGKKDLYLA SVFHATAFEL DTDGNPFDQD IYGREELRSP KLFYADHPFI FLVRDTQSGS LLFIGRLVRP KGDKMRDEL
Expression System E.coli
Grade & Purity > 90% pure
Molecular Weight 48.9 kDa (439 aa), confirmed by MALDI-TOF.
Tag/Conjugate His tag
Form & Buffer Supplied as a liquid in 20mM Tris-HCl buffer, pH 8.0, containing 10% glycerol.
Concentration 1 mg/ml

Storage & Safety

Storage Store at 4 deg C for short term storage (1/2 weeks). Aliquot and store at -20 deg C or - 70 deg C for long term storage. Avoid repeated freeze/thaw cycles.

General Information

Biological Significance Heat shock protein 47 (HSP47), also known as Colligin or Serpin H1, is a serpin which serves as a human chaperone protein for collagen. This protein is a member of the serpin superfamily of serine proteinase inhibitors. Its expression is induced by heat shock. The protein acts as a molecular chaperone facilitating the folding and assembly of procollagen molecules, retaining unfolded molecules within the ER, and assisting the transport of correctly folded-molecules from the ER to Golgi apparatus. Recombinant human HSP47/Colligin protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.

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Availability: In stock

Price: €169.35
Size: 100 ug
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