HTRA2/Omi antibody (10R-1022)

Mouse monoclonal HtrA2/Omi antibody

Synonyms Monoclonal HTRA2/Omi antibody, Anti-HTRA2/Omi antibody, High temperature requirement protein A2 antibody, HTRA2/Omi antibody, OMI antibody, mitochondrial antibody, EC 3.4.21.108 antibody, Serine protease 25 antibody, Omi stress-regulated endoprotease antibody, HTRA/Omi -2 antibody, High temperature requirement protein A2 antibody, HTRA2/Omi, HTRA2 antibody, Serine protease HTRA2 antibody, Serine proteinase OMI antibody, HTRA2 antibody, HTRA/Omi -2, HTRA/Omi 2, PRSS25 antibody, HTRA/Omi 2 antibody
Specificity Human
Cross Reactivity Human, Mouse
Applications ELISA, WB
Immunogen HtrA2/Omi antibody was raised in mouse using recombinant human HtrA2/Omi (134-458aa) purified from E. Coli as the immunogen.

Specifications

Host Mouse
Clone 1B3
Isotype IgG1 kappa
Source Anti-human HTRA2/Omi antibody, clone 1B3, is derived from hybridization of mouse SP2/0 myeloma cells with spleen cells from BALB/c mice immunized with a recombinant human HtrA2/Omi protein.
Method of Purification HTRA2/Omi antibody was purified by protein-G affinity chromatography
Form & Buffer Supplied as a liquid in PBS, pH 7.4, with 0.1% NaN3.
Concentration 1 mg/ml

Usage & Assay Information

Usage Recommendations WB: 1:500-1:2,000

Storage & Safety

Storage Store at 4 deg C for short term storage. Aliquot and store at -20 deg C for long term storage. Avoid repeated freeze/thaw cycles.

General Information

Biological Significance HTRA2/Omi is a mammalian serine protease at high temperatures and a chaperone at low temperature. The full-length HTRA2 is synthesized as a precursor protein and then targeted to the mitochondria where it is matured by the removal of the N-terminal 133 residues. Mature HTRA2 consists of a putative transmembrane domain; an inhibitor of apoptosis protein (IAP)-binding motif; a single C-terminal PDZ domain that mediates protein-protein interactions. Recently, HTRA2 has known to contribute both to caspase-dependent and caspase-independent cell death

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Availability: In stock

Price: €249.33
Size: 100 ul
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