Human CD27 ELISA kit (55R-2259)

ELISA kit for detection of CD27 (TNFRSF7) in the research laboratory

Synonyms Human TNFRSF7 ELISA kit
Specificity Human
Applications ELISA
Assay Information Sensitivity: 62.5 pg/ml-4000 pg/ml Sample types: Cell culture supernatants and serum

Specifications

Grade & Purity ELISA grade
Form & Buffer Kit contents:Lyophilized recombinant human CD27 standard, 96-well plate precoated with anti-human CD27 antibody, sample diluent buffer, Biotinylated anti-human CD27 antibody, antibody diluent buffer,ABC Complexand diluent buffer, TMB color developing agen

Usage & Assay Information

Usage Recommendations Optimal conditions to be determined by end user

Storage & Safety

Storage Store at 4 deg Cshort term (6 months); -20 deg Cfor long term. Avoid multiple freeze-thaw cycles

General Information

Biological Significance CD27 (also called TNFRSF7) is a tumor necrosis factor receptor. This gene is mapped to 12p13.31. The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is required for generation and long-term maintenance of T cell immunity. It binds to ligand CD70, and plays a key role in regulating B-cell activation and immunoglobulin synthesis. This receptor transduces signals that lead to the activation of NF-kappaB and MAPK8/JNK. Adaptor proteins TRAF2 and TRAF5 have been shown to mediate the signaling process of this receptor. CD27-binding protein(SIVA), a proapoptotic protein, can bind to this receptor and is thought to play an important role in the apoptosis induced by this receptor.

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Human CD27 ELISA Kit Protocol

Added: Jun 22, 2016

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Availability: In stock

Price: €503.07
Size: 1 kit
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