Human IgA protein (31R-AI001)
Purified Human IgA protein
Overview
Overview
| Synonyms | Immunoglobulin A protein |
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| Species | Human |
| Applications | User optimized |
Specifications
| Source | Human plasma |
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| Grade & Purity | > 96% pure |
| Molecular Weight | 160 kDa |
| Form & Buffer | 0.05M PO4 buffer, pH 7.5, with 0.15M NaCl, and 0.1% NaN3. |
| Concentration | Batch dependent - please inquire should you have specific requirements |
Storage & Safety
| Storage | Aliquot and store at -20 deg C. Avoid repeated freeze/thaw cycles |
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| Biohazard Information | This product contains sodium azide as preservative. Although the amount of sodium azide is very small appropriate care must be taken when handling this product. |
General Information
| Biological Significance | IgA antibodies play a central role in defence against pathogens by preventing adhesion penetration. Reduced levels can be due to a congenital deficiency, to certain disorders (IgG myeloma and lymphoma) or in response to certain drugs. Very high levels of monoclonal IgA are associated with IgA myeloma, benign blood globulin disorders in elderly patients and certain severe infectious diseases. |
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