Human IgG2 protein (31-AI18)
Purified Human IgG2 protein
Overview
Overview
| Synonyms | Human IgG2 Whole Molecule, Immunoglobulin G2 Protein |
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| Species | Human |
| Applications | User optimized |
Specifications
| Source | Human myeloma plasma |
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| Grade & Purity | > 95% pure |
| Molecular Weight | 146 kDa |
| Form & Buffer | 20mM phosphate, pH 7.4, with 150mM NaCl and 0.05% NaN3. |
| Concentration | Batch dependent - please inquire should you have specific requirements |
Storage & Safety
| Storage | Aliquot and store at -20 deg C. Avoid repeated freeze/thaw cycles. |
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| Biohazard Information | This product contains sodium azide (NaN3), a chemical highly toxic in pure form. At product concentrations, though not classified as hazardous, NaN3 may react with lead and copper plumbing to form highly explosive build-ups of metal azides. Upon disposa |
General Information
| Biological Significance | IgG2 is the only IgG subclass which passes through the placenta at a level generally lower than that found in the mother. A deficiency of IgG2 indicates a poor antibody response to bacterial polysaccharides and can lead to increased susceptibility to infections caused by encapsulated bacteria. |
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