Human IgG3 protein (31R-1058)
Purified native IgG3 protein
Overview
Overview
| Synonyms | IgG3 Whole Molecule, Immunoglobulin G3 Protein |
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| Species | Human |
| Protein Type | Native |
| Applications | ELISA, SDS-PAGE, WB |
Specifications
| Source | Pooled normal Human serum |
|---|---|
| Grade & Purity | > 95% pure |
| Form & Buffer | Supplied in liquid form in PBS buffer |
Storage & Safety
| Storage | Store at 4 deg C in a working aliquot for 1 week. For long term storage, aliquot and freeze at -20 to -80 deg C, avoid repeat freeze/thaw cycles |
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| Biohazard Information | Raw materials ethically sourced from healthy donors, however, this product has NOT been tested for infectious diseases. Please handle as potentially hazardous, with full laboratory safety precautions. |
General Information
| Biological Significance | IgG is a monomeric immunoglobulin, built of two heavy chains gamma and two light chains. Each molecule has two antigen binding sites. This is the most abundant immunoglobulin and is approximately equally distributed in blood and in tissue liquids, constituting 75% of serum immunoglobulins.It can bind to many kinds of pathogens, for example viruses, bacteria, and fungi, and protects the body against them by complement activation (classic pathway), opsonization for phagocytosis and neutralisation of their toxins. There are 4 subclasses: IgG1 (66%), IgG2 (23%), IgG3 (7%) and IgG4 (4%). |
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