Human IgM protein (31R-1015)
Purified Human IgM protein
Overview
Overview
| Synonyms | Human Immunoglobulin M protein |
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| Species | Human |
Specifications
| Source | Normal Human Serum/Plasma was obtained from healthy donors of US origin. |
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| Grade & Purity | > 95% pure |
| Form & Buffer | Clear, colorless liquid, 0.2 um filtered, containing 10 mM Sodium Phosphate, 0.15 M Sodium Chloride and 0.05% (w/v) Sodium Azide. Protease/IgG free. |
Storage & Safety
| Storage | Store at 2-8 deg C. |
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| Biohazard Information | Donor serum was tested by FDA approved methods and found negative for antibodies to HIV1/HIVII and HCV. Donor serum was tested by FDA approved methods and found negative for HBsAg, HIV-1 RNA, HCV RNA and Syphilis. |
General Information
| Biological Significance | IgM is found in normal plasma at a concentration of 1.2 to 4.0 mg/ml. It is the first immunoglobulin produced during the immune response, the first antibody in neonates, and is involved in pathogenesis of autoimmune diseases. A diminished level of IgM is associated with Wiskott-Aldrich syndrome. |
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