Human Macrophage antibody (10R-M102a)

Mouse monoclonal Macrophage L1 protein Calprotectin antibody

Synonyms Monoclonal Human Macrophage antibody, Anti-Human Macrophage antibody, Calprotectin antibody, Macrophage L1 protein Calprotectin antibody, L1 protein antibody
Cross Reactivity Baboon, cat, dog, guinea pig, human, monkey, mouse, pig, rat
Applications IHC-F, IHC-P
Immunogen Macrophage L1 protein Calprotectin antibody was raised in mouse using affinity purified monocyte membrane preparation as the immunogen.

Images

Immunohistochemical staining using Human Macrophage antibody (10R-M102a)

Formalin-fixed, paraffin-embedded human tonsil stained with Macrophage antibody using peroxidase-conjugate and AEC chromogen. Note cytoplasmic staining of macrophages.

Specifications

Host Mouse
Clone MAC 387
Isotype IgG1
Method of Purification Human Macrophage antibody was purified by Protein G chromatography.
Form & Buffer 10mM PBS, pH 7.4, with 0.2% BSA and 0.09% NaN3.
Concentration 0.2 mg/ml

Usage & Assay Information

Usage Recommendations IHC-F: 1:1,000, IHC-P: 1:1,000

Storage & Safety

Storage Store at 4 deg C.
Biohazard Information This product contains sodium azide as preservative. Although the amount of sodium azide is very small appropriate care must be taken when handling.

General Information

Biological Significance Calprotectin is a 36 kDa calcium and zinc binding protein. It accounts for 60% of neutrophils cytosol. In vitro studies show it has bacteriostatic and fungistatic properties. It is resistant to enzymatic degradation, and can be easily measured in faeces. Measurement of faecal calprotectin is a biochemical test for inflammatory bowel disease. It replaces the need for invasive colonoscopy or radio-labelled white cell scanning in many clinical scenarios.

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Images

  • Immunohistochemical staining using Human Macrophage antibody (10R-M102a) | Formalin-fixed, paraffin-embedded human tonsil stained with Macrophage antibody using peroxidase-conjugate and AEC chromogen. Note cytoplasmic staining of macrophages.

Availability: In stock

Price: €475.13
Size: 200 ug
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