Human sCD153 ELISA kit (55R-2257)
ELISA kit for the detection of sCD153 in the research laboratory
Overview
Overview
| Synonyms | Human sCD153 ELISA kit, CD153 ELISA kit, CD30L ELISA kit, CD30LG ELISA kit, MGC138144 ELISA kit, CD153 antigen ELISA kit |
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| Applications | ELISA |
| Assay Information | Assay Time : 1-5h, Sample Volume : 50-100ul, Detection Wavelengt : 450 nm |
Storage & Safety
| Storage | Store at 2-8 deg C |
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General Information
| Biological Significance | The human CD30 ligand, CD153, is a 40 kDa Type II transmembrane glycoprotein. It interacts with its receptor, CD30, as a homotrimer Soluble trimeric CD153 binds to membrane-anchored CD30 with a relatively high affinity and is very effective in triggering cell death and TNF alpha. CD153 is a member of the TNF superfamily which is primarilyexpressed by activated T cells, B cells and monocytes. Its function in programmed cell death has been proven, as well as its involvement in disorders like a variety of lymphoid malignancies like Hodgkin’s disease and anaplastic large cell lymphoma. |
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