IFITM1 antibody (70R-13775)

Affinity purified Rabbit polyclonal IFITM1 antibody

Synonyms Polyclonal IFITM1 antibody, Anti-IFITM1 antibody, Interferon-induced Transmembrane Protein 1 antibody, IFITM1, IFITM 1 antibody, IFITM 1, IFI17 antibody, Interferon induced Protein 17 antibody, IFITM-1 antibody, IFITM-1
Applications IHC-F, IHC-P, WB
Immunogen IFITM1 antibody was raised in Rabbit using a synthetic peptide corresponding to a sequence at the N-terminal of human IFITM1 as the immunogen

Images

Immunohistochemical staining using IFITM1 antibody (70R-13775)

Immunohistochemistry of paraffin-embedded section of Human intestinal cancer tissue

Specifications

Host Rabbit
Isotype IgG
Method of Purification IFITM1 antibody was purified by affinity chromatography
Form & Buffer Supplied in lyophilized form

Usage & Assay Information

Usage Recommendations Optimal conditions to be determined by the end user

Storage & Safety

Storage Store at 4 deg C for short term storage. For long term storage aliquot and store at -20 deg C, avoid repeated freeze/thaw cycles.

General Information

Biological Significance IFITM1 activity is required for primordial germ cells (PGCs) transit from the mesoderm into the endoderm, and that it appears to act via a repulsive mechanism, such that PGCs avoid Ifitm1-expressing tissues. It is mapped to Chr11 and belongs to the family of interferon-induced transmembrane proteins (Ifitm/mil/fragilis), which encodes cell surface proteins that may modulate cell adhesion and influence cell differentiation. Interferon-inducible membrane proteins of approximately 17 kDa have been suggested to play a role in the antiproliferative activity of interferons based on their pattern of induction in interferon-sensitive and -resistant cell lines and the ability of a membrane fraction enriched in 17-kDa proteins to inhibit cell growth.

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Images

  • <div><font face=Calibri size=2>Immunohistochemical staining using IFITM1 antibody (70R-13775)</font></div>     | Immunohistochemistry of paraffin-embedded section of Human intestinal cancer tissue
  • <div><font face=Calibri size=2>Western Blot analysis using IFITM1 antibody (70R-13775)</font></div>     | Lane 1: SW620 Cell Lysate; Lane 2: CEM Cell Lysate

Availability: In stock

Price: €377.10
Size: 100 ug
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