IFN beta protein (30R-AB026)

Purified recombinant Human IFN beta protein

Synonyms Leukocyte interferon antibody, RMMB1 antibody, Interferon beta antibody, Type I interferon antibody, B cell interferon antibody
Species Human
Protein Type Recombinant
Applications User optimized

Specifications

Residues Region of IFN Beta protein corresponding to amino acids MSYNLLGFLQ RSSNFQCQKL LWQLNGRLEY CLKDRMNFDI PEEIKQLQQF QKEDAALTIY EMLQNIFAIF RQDSSSTGWN ETIVENLLAN VYHQINHLKT VLEEKLEKED FTRGKLMSSL HLKRYYGRIL HYLKAKEYSH CAWTIVRVEI LRNFYFINRL TGYLRN.
Expression System CHO cells
Grade & Purity > 95% pure
Molecular Weight 20 kDa
Form & Buffer Lyophilized from 10mM sodium citrate, with 100mM NaCl, and 10mM Sucrose. Reconstitute in water to a concentration of 0.1-1.0mg/ml. DO NOT VORTEX. For extended storage, dilute further in a buffer containing a carrier protein (ie: 0.1% BSA).

Usage & Assay Information

Bioactivity Assay#1: The biological activity of PeproTech's human IFN-gamma was based on analysis using the WISH cell line with VSV as the challenge virus. The specific activitywas determined to be >5 x 10 8 units/mg, Assay#2: Measured by its ability to induce apo

Storage & Safety

Storage Store at 4 deg C until reconstitution. Following reconstitution aliquot and freeze at -20 deg C for long term storage. Avoid repeated freeze/thaw cycles.
Endotoxin Levels Endotoxin level is less than 0.1 ng per ug (1 EU/ug).

General Information

Biological Significance Proteins of this family play an important role in inducing non-specific resistance against a broad range of viral infections. They also affect cell proliferation and modulate immune responses. Produced by peripheral blood leukocytes and lymphoblastoid cells, IFNa is an acid stable molecule that signals through IFNa/betaR, which is also used by IFNbeta. Both IFNs have similar anti-viral activity and regulate expression of MHC class I antigens. IFNa contains four highly conserved cysteine residues which form two disulfide bonds, one of which is necessary for biological activity.

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Availability: In stock

Price: €211.69
Size: 20 ug
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