IFN gamma protein (30R-2267)

Purified recombinant Human IFN gamma protein

Synonyms Interferon-gamma protein
Specificity Human
Species Human
Protein Type Recombinant
Applications FC
Assay Information A test is defined as the amount (ug) of antibody that will stain a cell sample in a final volume of 100 ul. Cell number should be determined empirically but can range from 105 to 108 cells/test. It is recommended that the antibody be carefully titrated for optimal performance in the assay of interest.

Specifications

Expression System E.coli
Grade & Purity > 98% pure
Molecular Weight 16 kDa
Form & Buffer Supplied as a sterile liquid with phosphate buffered saline, pH7.2, 0.22 um filtered.
Concentration 5 ul (0.125 ug)/test

Usage & Assay Information

Usage Recommendations FC: = 0.5 ug/test
Bioactivity The ED50 of this protein, as measured by EMC virus protection assay using A549 cells, is less than or equal to 175 pg/ml. This corresponds to a specific activity ofgreater than or equal to 5.7 x 10e6 Units/mg.

Storage & Safety

Storage Store at -70 deg C or less.
Endotoxin Levels Less than 0.01 ng/ug cytokine as determined by the LAL assay.

General Information

Biological Significance Human IFN gamma is an ~20 kDa factor produced by activated T, B and NK cells and is an anti-viral and anti-parasitic cytokine. IFN gamma in synergy with other cytokines, such as TNF alpha, inhibits proliferation of normal and transformed cells. Immunomodulatory effects of IFN gamma are exerted on a wide range of cell types expressing the high affinity receptors for IFN-gamma. Glycosylation of IFN gamma does not affect its biological activity.

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Availability: In stock

Price: €265.85
Size: 100 ug
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