IFNa2 protein (Mouse) (30R-2184)

Purified recombinant Mouse IFNa2 protein

Synonyms IFNa-2 protein, IFNa 2 protein, IFNa2, IFN-a2 protein, IFNa-2, IFNa 2, Interferon- alpha 2 protein
Specificity Mouse
Species Mouse
Protein Type Recombinant
Applications ELISA
Assay Information

Specifications

Expression System E.coli
Grade & Purity > 98% pure
Method of Purification IFNa2 protein was purified by affinity chromatography.
Molecular Weight 18 kDa
Form & Buffer Supplied as a sterile liquid with 50mM NaAc, 0.1M NaCl, 0.5%BSA, pH 5.0
Concentration 500 ug/ml

Usage & Assay Information

Bioactivity The recombinant mouse IFN- alpha2 has been tested for inhibition of the cytopathic effect of EMC virus onL929 cells. The ED50 for this effect is typically 0.1 ng/ml, corresponding to a specific activity of 1 x 107 U/mg.

Storage & Safety

Storage Store at -70 deg C or less.
Endotoxin Levels Less than 0.01 ng/ug cytokine as determined by the LAL assay.

General Information

Biological Significance IFN- alpha 2 is a type I interferon, previously known as B-cell interferon, leukocyte interferon, lymphoblast interferon, and pH2-stable interferon. IFN- alpha 2 is one of at least 23 different known variants of IFN- alpha. The individual proteins have molecular masses between 19-26 kDa and consist of proteins with lengths of 156-166 and 172 amino acids. IFN- alpha forms are produced by monocytes/macrophages, lymphoblastoid cells, fibroblasts, and a number of different cell types following induction by viruses, nucleic acids, glucocorticoid hormones, and low-molecular weight substances. IFN- alpha 2 demonstrates antiviral, antiparasitic, antiproliferative activities.

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Price From: Price: €184.05
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