IGF1 protein (Rat) (His tag) (80R-3196)
Purified recombinant IGF1 protein (Rat) (His tag)
Overview
Overview
| Synonyms | Insulin like growth factor I protein, IGF 1 protein, IGF-1 protein, somatomedin C protein |
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| Species | Rat |
| Protein Type | Recombinant |
| Applications | ELISA, SDS-PAGE, WB |
Specifications
| Expression System | E.coli |
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| Grade & Purity | > 90% pure |
| Molecular Weight | 13 kDa |
| Tag/Conjugate | His tag |
| Form & Buffer | Supplied in liquid form in PBS buffer with 20 mM GSH |
Storage & Safety
| Storage | Store at 4 deg C in a working aliquot for 1 week. For long term storage, aliquot and freeze at -20 to -80 deg C, avoid repeat freeze/thaw cycles |
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General Information
| Biological Significance | The insulin-like growth factors such as IGF1, isolated from plasma, are structurally and functionally related to insulin but have a much higher growth-promoting activity. May be a physiological regulator of-2-deoxy-D-glucose (2DG) transport and glycogen synthesis in osteoblasts. Stimulates glucose transport in rat bone-derived osteoblastic (PyMS) cells and is effective at much lower concentrations than insulin, not only regarding glycogen and DNA synthesis but also with regard to enhancing glucose uptake. |
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