IL1 alpha antibody (70R-13917)
Affinity purified Goat polyclonal IL1 alpha antibody
Overview
Overview
| Synonyms | Polyclonal IL1 alpha antibody, Anti-IL1 alpha antibody, Lymphocyte-activating factor antibody, Leukocyte Endogenous Mediator antibody, Mononuclear Cell Factor antibody, Hematopoietin-1 antibody, Endogenous Pyrogen antibody, LEM antibody, Interleukin 1 alpha antibody, EP antibody, MCF antibody, LAF antibody, IL-1 alpha antibody |
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| Applications | IHC-P, WB |
| Immunogen | IL1 alpha antibody was raised in Rabbit using a synthetic peptide corresponding to a sequence at the C-terminal of Rabbit IL1 alpha as the immunogen |
Images
Western Blot analysis using IL1 alpha antibody (70R-13917)
Lane 1: Mouse Spleen Tissue Lysate; Lane 2: Mouse Thymus Tissue Lysate
Specifications
| Host | Rabbit |
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| Isotype | IgG |
| Method of Purification | IL1 alpha antibody was purified by affinity chromatography |
| Form & Buffer | Supplied in lyophilized form |
Usage & Assay Information
| Usage Recommendations | Optimal conditions to be determined by the end user |
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Storage & Safety
| Storage | Store at 4 deg C for short term storage. For long term storage aliquot and store at -20 deg C, avoid repeated freeze/thaw cycles. |
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General Information
| Biological Significance | IL1a is a non-secreted proinflammatory cytokine produced in a variety of cells including monocytes, tissue macrophages, keratinocytes and other epithelial cells. Both IL1a and IL1beta binds to the same receptor and has similar if not identical biological properties. These cytokines have a broad range of activities including, stimulation of thymocyte proliferation, by inducing IL2 release, B-cell maturation and proliferation, mitogenic FGFlike activity and the ability to stimulate the release of prostaglandin and collagenase from synovial cells. However, whereas IL1beta is a secreted cytokine, IL1a is predominantly a cell-associated cytokine. |
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