IL1 beta antibody (70R-12273)
Rabbit polyclonal IL1 beta antibody
Overview
Overview
| Synonyms | Polyclonal IL1 beta antibody, anti-IL1 beta antibody, IL1 beta antibody, Interluekin 1 beta antibody, IL-1 beta antibody, IL1 beta, IL beta-1, Interluekin-1 beta antibody, IL 1 beta antibody, IL beta 1, IL beta 1 antibody, IL beta-1 antibody |
|---|---|
| Cross Reactivity | Mouse |
| Applications | Neutralization, WB |
| Immunogen | IL1 beta antibody was raised in Rabbit using E coli expressed murine IL-1beta as the immunogen. |
Images
Western Blot analysis using IL1 beta antibody (70R-12273)
Western blot analysis using recombinant murine IL1-beta. Lane 1: 10ng. Lane 2: 50ng. Lane 3: 250ng.
Specifications
| Host | Rabbit |
|---|---|
| Isotype | IgG |
| Method of Purification | IL1 beta antibody was purified by affinity chromatography |
| Form & Buffer | Supplied in PBS buffer, pH 7.2, containing 30% glycerol, 0.5%BSA and 0.01% thimerosal |
| Concentration | 500 ug/ml |
Usage & Assay Information
| Usage Recommendations | WB: 0.5-4 ug/ml |
|---|
Storage & Safety
| Storage | Store at 4 deg C for short term storage. Aliquot and store at -20 deg C for long term storage. Avoid repeated freeze/thaw cycles. |
|---|
General Information
| Biological Significance | IL-1 beta is a proinflammatory cytokine produced in a variety of cells including monocytes, tissue macrophages, keratinocytes and other epithelial cells. Both IL-1 alpha and IL-1 beta binds to the same receptor and has similar if not identical biological properties. These cytokines have a broad range of activities including, stimulation of thymocyte proliferation, by inducing IL-2 release, B-cell maturation and proliferation, mitogenic FGF-like activity and the ability to stimulate the release of prostaglandin and collagenase from synovial cells. However, whereas IL-1 beta is a secreted cytokine, IL-1 alpha is predominantly a cell-associated cytokine. Recombinant murine IL-1 beta is a 17.5 kDa protein containing 153 amino acid residues. |
|---|
Reviews
You need to be logged in to write a review. Please login here
Sorry there are currently no reviews for this product