IL10 protein (30R-AI075)

Purified recombinantRat IL10 protein

Synonyms CSIF protein, B-TCGF protein, TGIF protein, IL 10 protein, Interleukin 10 protein, IL-10 protein, IL10, IL 10, IL-10 protein, IL-10
Cross Reactivity Cross reacts with mouse, rat.
Species Rat
Protein Type Recombinant
Applications User optimized

Specifications

Residues Region of IL10 protein corresponding to amino acids SKGHSIKGDN NCTHFPVSQT HMLRELRAAF SQVKTFFQKK DQLDNIVLTD SLLQDFKGYL GCQALSEMIK FYLVEVMPQA ENHGPEIKEH LNSLGEKLKT LWIQLRRCHR FLPCENKSKA VEQVKNDFNK LQDKGVYKAM NEFDIFINCI EAYVTLKMKN
Expression System E.coli
Grade & Purity > 98% pure
Molecular Weight 18.7 kDa
Form & Buffer Lyophilized from 20mM Na3PO4, pH 7.0. Reconstitute in water to a concentration of 0.1 - 1.0 mg/ml.

Usage & Assay Information

Bioactivity The ED50 as determined by the dose-dependent inhibition of antigen-specific T cell proliferation is less than 10ng/ml.

Storage & Safety

Storage Store at 4 deg C until reconstitution. Following reconstitution aliquot and freeze at -20 deg C for long term storage. Avoid repeated freeze/thaw cycles.
Endotoxin Levels Endotoxin level is less than 0.1 ng per ug (1 EU/ug).

General Information

Biological Significance IL-10 is an immunosuppressive cytokine produced by a variety of mammalian cell types including macrophages, monocytes, T cells, B cells and keratinocytes. IL-10 inhibits the expression of proinflammatory cytokines such as IL-1 and TNF-a. Like IL-4, IL-10 enhances humoral immune responses and attenuates cell-mediated immune reactions. Human IL-10 is active on murine cells, but murine IL-10 is inactive on human cells. Recombinant Rat IL-10 is an 18.7 kDa protein of 160 amino acid residues.

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Availability: In stock

Price: €185.94
Size: 10 ug
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