IL12 antibody (10R-I125B)
Rat monoclonal IL12 antibody
Overview
Overview
| Synonyms | Monoclonal IL12 antibody, Anti-IL12 antibody, IL 12 antibody, CLMF antibody, IL-12 antibody, TSF antibody, IL-12 antibody, Cytotoxic lymphocyte maturation factor antibody, CTL maturation factor antibody, IL 12, IL12, IL-12, NKSF antibody, TCMF antibody, Interleukin 12 antibody |
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| Specificity | Murine IL-12 |
| Cross Reactivity | To be determined by end-user |
| Applications | ELISA, Inhibition, WB |
| Immunogen | IL12 antibody was raised in rat using highly pure recombinant Mouse IL-12 as the immunogen. |
Specifications
| Host | Rat |
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| Clone | M912296 |
| Isotype | IgG1 kappa |
| Molecular Weight | 75 kDa (predicted detection band MW) |
| Form & Buffer | Lyophilized from PBS. |
Usage & Assay Information
| Usage Recommendations | ELISA: 4-8 ug/ml, Inhibition: 0.16-0.24 ug/ml, WB: 2-4 ug/ml |
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Storage & Safety
| Storage | Store at -20 deg C until reconstitution. Following reconstitution product may be stored at 4 deg C in the short term. For long term storage aliquot and freeze at -20 deg C. Avoid repeated freeze/thaw cycles. |
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General Information
| Biological Significance | IL12 is a potent regulator of cell mediated immune responses and it induces IFN-gamma production by NK and T cells. It is produced by activated monocytes/macrophage cells, B lymphocytes and connective tissue type mast cells. Among its biological activities IL12 promotes the growth and activity of activated NK, CD4+ and CD8+ cells and induces the development of IFN-gamma producing Th1 cells. |
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