IL12 protein (30R-2509)

Purified recombinant Rat IL12 protein

Synonyms TSF protein, IL 12, Cytotoxic lymphocyte maturation factor (CLMF) protein, NKSF protein, CTL maturation factor (TCMF) protein, Edodekin-alpha protein, IL-12 protein, IL-12 protein, IL-12, IL12, IL 12 protein
Species Rat
Protein Type Recombinant

Specifications

Expression System Sf-9 insect cells
Grade & Purity > 95% pure
Method of Purification IL12 protein was purified using a a proprietary chromatographic technique.
Molecular Weight 70 kDa
Form & Buffer Supplied in lyophilized form from 1 mg/ml solution with no additives

Usage & Assay Information

Bioactivity The ED50 range is 001-0.005 ng/ml, as determined by the dose-dependent secretion of IFN-gamma from PHA and IL-12 activated mouse splenocytes that has been co-stimulated with PMA

Storage & Safety

Storage Store at 4 deg C for short term storage. Aliquot and store at -20 deg C for long term storage. Avoid repeated freeze/thaw cycles.
Endotoxin Levels <0.1 ng/ug

General Information

Biological Significance IL-12 is a potent regulator of cell mediated immune responses and in induces IFN gamma production by NK and T cells. It is produced by activated monocytes/macrophage cells, B-lymphocytes, and connective tissue type mast cells. Among its biological activities, IL-12 promotes the growth and activity of activated NK, CD4+, and CD8+ cells and induce the development of IFN gamma producing Th1 cells.

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Availability: In stock

Price: €256.03
Size: 10 ug
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