IL12P40 protein (His tag) (80R-2225)
Purified recombinant Human IL12P40 Protein (His tag)
Overview
Overview
| Synonyms | IL-12B protein, NKSF protein, NKSF2 protein, CLMF protein, IL12P40, ILP40-12, interleukin 12 subuit beta protein, ILP40-12 protein, ILP40 12, ILP40 12 protein, CLMF2 protein |
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| Species | Human |
| Protein Type | Recombinant |
| Applications | SDS-PAGE |
Images
Coomassie Blue stained SDS-PAGE of IL12P40 protein (His tag) (80R-2225)
Figure annotation denotes ug of protein loaded and % gel used.
Specifications
| Residues | ADPIWELKKD VYVVELDWYP DAPGEMVVLT CDTPEEDGIT WTLDQSSEVL GSGKTLTIQV KEFGDAGQYT CHKGGEVLSH SLLLLHKKED GIWSTDILKD QKEPKNKTFL RCEAKNYSGR FTCWWLTTIS TDLTFSVKSS RGSSDPQGVT CGAATLSAER VRGDNKEYEY SVECQEDSAC PAAEESLPIE VMVDAVHKLK YENYTSSFFI RDIIKPDPPK NLQLKPLKNS RQVEVSWEYP DTWSTPHSYF SLTFCVQVQG KSKREKKDRV FTDKTSATVI CRKNASISVR AQDRYYSSSW SEWASVPCSH HHHHH |
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| Expression System | Hi-5 cells |
| Grade & Purity | > 90% pure |
| Molecular Weight | 35.8 kDa |
| Tag/Conjugate | His tag |
| Form & Buffer | Supplied in liquid form in 20mM Tris-HCl buffer, pH 8.0, containing 2mM DTT, 20% glycerol, 100mM NaCl, 0.1mM PMSF. |
| Concentration | 250 ug/ml |
Storage & Safety
| Storage | Store at 4 deg C for short term storage. Aliquot and store at -20 deg C for long term storage. Avoid repeated freeze/thaw cycles. |
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General Information
| Biological Significance | IL12P40 is a subunit of the heterodimeric cytokine interleukin 23 (IL23). IL23 is composed of this protein and the p40 subunit of interleukin 12 (IL12B). The receptor of IL23 is formed by the beta 1 subunit of IL12 (IL12RB1) and an IL23 specific subunit, IL23R. Both IL23 and IL12 can activate the transcription activator STAT4, and stimulate the production of interferon-gamma (IFNG). |
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