IL13 protein (30R-2512)
Purified recombinant Rat IL13 protein
Overview
Overview
| Synonyms | IL-13 protein, MGC116788 protein, IL 13, MGC116786 protein, IL-13 protein, ALRH protein, IL13, IL-13, IL 13 protein, P600 protein, BHR1 protein, MGC116789 protein, NC30 protein |
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| Species | Rat |
| Protein Type | Recombinant |
Specifications
| Expression System | E.coli |
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| Grade & Purity | > 95% pure |
| Method of Purification | IL13 protein was purified using a a proprietary chromatographic technique. |
| Molecular Weight | 12.7 kDa |
| Form & Buffer | Supplied in lyophilized form with no additives |
Usage & Assay Information
| Bioactivity | The ED50 as determined by the dose-dependent stimulation of the proliferation of human TF-1 cells was typically 2-6 ng/ml |
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Storage & Safety
| Storage | Store at 4 deg C for short term storage. Aliquot and store at -20 deg C for long term storage. Avoid repeated freeze/thaw cycles. |
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| Endotoxin Levels | <0.1 ng/ug |
General Information
| Biological Significance | IL-13 is an immunoregulatory cytokine produced mainly by T helper 2 cells, but also by mast cells and NK cells. IL-13 is a unique cytokine having similar structural features and functional characteristics as IL-4, but only shares ~30% homolog with the IL-4 sequence. IL-13 inhibits IL-1 beta, IL-6, IL-8, and TNF-alpha resulting in anti-inflammatory effects on monocytes and macrophages. IL-13 also induces B cells to proliferate and modulating TH2 cell development. |
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