IL15 protein (Mouse) (30R-AI011)
Purified recombinant Mouse IL15 protein
Overview
Overview
| Synonyms | IL-15 protein, IL15, IL-T protein, IL 15 protein, IL-15 protein, IL-15, Interleukin 15 protein, IL 15 |
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| Species | Mouse |
| Protein Type | Recombinant |
| Applications | User optimized |
Specifications
| Residues | Region of IL15 protein corresponding to amino acids MNWIDVRYDL EKIESLIQSI HIDTTLYTDS DFHPSCKVTA MNCFLLELQV ILHEYSNMTL NETVRNVLYL ANSTLSSNKN VAESGCKECE ELEEKTFTEF LQSFIRIVQM FINTS. |
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| Expression System | E.coli |
| Grade & Purity | > 98% pure |
| Molecular Weight | 13.3 kDa |
| Form & Buffer | Lyophilized from 10mM Na3PO4, pH 8.0. Reconstitute with distilled water to a concentration of 0.5-1.0mg/ml. |
Usage & Assay Information
| Bioactivity | The ED50 was determined by the stimulation of the proliferation of Mouse CTLL-2 cells is 2 x 10^5 units/mg. |
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Storage & Safety
| Storage | Store at 4 deg C until reconstitution. Following reconstitution aliquot and freeze at -20 deg C for long term storage. Avoid repeated freeze/thaw cycles. |
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| Endotoxin Levels | Endotoxin level is less than 0.1 ng per ug (1 EU/ug). |
General Information
| Biological Significance | IL15 is an immunomodulating cytokine that stimulates the proliferation of T lymphocytes and shares many biological properties with IL2. IL15 exerts its biological activites primarily on T cells. It is also essential in the development, survival and activation of NK cells. Increased expression of IL15 has been implicated with rheumatoid arthritis, inflammatory bowl disease and diseases affiliated with retroviruses HIV and HTLV-I. Human IL15 is biologically active on mouse cells as measured by the dose-dependent stimulation of the proliferation of mouse CTLL cells. |
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