IL16 protein (His tag) (80R-1046)
Purified recombinant Human IL16 protein
|Synonyms||FLJ42735 protein, HGNC:5980 protein, IL-16 protein, Interleukin 16 precursor protein, IL-16, Lymphocyte chemoattractant factor protein, prIL-16 protein, IL 16 protein, PrIL16 protein, FLJ44234 protein, IL 16 protein, LCF protein, IL 16, IL16, FLJ16806 protein, , HST19289 protein|
Coomassie Blue stained SDS-PAGE of IL16 protein (His tag) (80R-1046)
Figure annotation denotes ug of protein loaded and % gel used.
|Residues||502-631 amino acids: MGSSHHHHHH SSGLVPRGSH MPDLNSSTDS AASASAASDV SVESTAEATV CTVTLEKMSA GLGFSLEGGK GSLHGDKPLT INRIFKGAAS EQSETVQPGD EILQLGGTAM QGLTRFEAWN IIKALPDGPV TIVIRRKSLQ SKETTAAGDS|
|Grade & Purity||> 95% pure|
|Molecular Weight||15.5 kDa (150aa), confirmed by MALDI-TOF.|
|Form & Buffer||Supplied as a liquid in 20mM Tris, pH 8.0, containing 1mM DTT, and 10% glycerol.|
Storage & Safety
|Storage||Store at 4 deg C for short term storage (1/2 weeks). Aliquot and store at -20 deg C or - 70 deg C for long term storage. Avoid repeated freeze/thaw cycles.|
|Biological Significance||Interleukin-16 (IL16) is an immunomodulatory cytokine, which induces lymphocyte migration, expression of proinflammatory IL-1beta, IL6 and tumour necrosis factor-alpha (TNF alpha), and modulates apoptosis. This protein is a pleiotropic cytokine that functions as a chemoattractant, a modulator of T cell activation, and an inhibitor of HIV replication. The signaling process of this cytokine is mediated by CD4. Also, several central nervous system diseases and may play a role in promoting inflammatory responses. Recombinant human IL16, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.|
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