IL17E protein (30R-AI015)

Purified recombinant Human IL17E protein

Synonyms IL17E, ILE-17, ILE-17 protein, IL-17E protein, Interleukin 17E protein, ILE 17, ILE 17 protein
Species Human
Protein Type Recombinant
Applications User optimized

Specifications

Residues Region of IL17E protein corresponding to amino acids MYSHWPSCCP SKGQDTSEEL LRWSTVPVPP LEPARPNRHP ESCRASEDGP LNSRAISPWR YELDRDLNRL PQDLYHARCL CPHCVSLQTG SHMDPRGNSE LLYHNQTVFY RRPCHGEKGT HKGYCLERRL YRVSLACVCV RPRVMG.
Expression System E.coli
Grade & Purity > 98% pure
Molecular Weight 33.8 kDa
Form & Buffer Lyophilized from 10 mM CH3COOH. Reconstitute in water to a concentration of 0.1 - 1.0 mg/ml.

Usage & Assay Information

Bioactivity Determined by its ability to induce IL-8 in human PBMCs using a concentration range of 10-100ng.

Storage & Safety

Storage Store at 4 deg C until reconstitution. Following reconstitution aliquot and freeze at -20 deg C for long term storage. Avoid repeated freeze/thaw cycles.
Endotoxin Levels Endotoxin level is less than 0.1 ng per ug (1 EU/ug).

General Information

Biological Significance IL17E is a disulfide-linked homodimer of two 145 amino acid polypeptide chains. It belongs to the IL17 family of structurally-related cytokines that share a highly conserved C-terminal region, but differ from one another in their N-terminal regions and in their distinct biological roles. The six known members of this family, IL17A through IL17F, are secreted as homodimers. IL17E stimulated secretion of IL8, and induces activation of the transcription factor NK- kb in cells that express the IL17BR receptor.

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Availability: In stock

Price: €211.69
Size: 25 ug
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