IL18 protein (30R-1071)
Purified recombinant Human IL18 protein
|Synonyms||IFN gamma inducing factor protein, IFN-gamma-inducing factor protein, , IL-18 protein, Interleukin-18 protein, Interferon gamma inducing factor protein, IGIF protein, IL-18 protein, IL18 protein protein, IL 1g protein, Interleukin-18 protein, Interleukin-1 gamma protein, IL1gamma protein, IL18, Interferon-gamma-inducing factor protein, IL1 gamma protein, IL 18 protein, IL 1 gamma protein, IL 18 protein, IL-18, Interleukin18 protein, Interleukin 1 gamma protein, Iboctadekin protein, IL1F4 protein, IL18 protein, IL1g protein, IL 18, Interleukin 18 protein, IL-1 gamma protein|
Coomassie Blue stained SDS-PAGE of IL18 protein (30R-1071)
Figure annotation denotes ug of protein loaded and % gel used.
|Residues||MYFGKLESKL SVIRNLNDQV LFIDQGNRPL FEDMTDSDCR DNAPRTIFII SMYKDSQPRG MAVTISVKCE KISTLSCENK IISFKEMNPP DNIKDTKSDI IFFQRSVPGH DNKMQFESSS YEGYFLACEK ERDLFKLILK KEDELGDRSI MFTVQNED|
|Grade & Purity||> 95% pure|
|Molecular Weight||18.3 kDa (158aa), confirmed by MALDI-TOF.|
|Form & Buffer||Supplied as a liquid in PBS, pH 7.4.|
Storage & Safety
|Storage||Store at 4 deg C for short term storage (1/2 weeks). Aliquot and store at -20 deg C or - 70 deg C for long term storage. Avoid repeated freeze/thaw cycles.|
|Endotoxin Levels||< 1.0 EU per ug of protein (determined by LAL method)|
|Biological Significance||Interleukin 18 (IL-18), previously known as interferon-gamma (IFN-gamma)-inducing factor, is an activator of NK cells and a co-inducer of Th1 cytokines. IL-18 is produced from Kupffer cells, activated macrophages, keratinocytes, intestinal epithelial cells, osteoblasts, adrenal cortex cells and murine diencephalon. IL-18 was expressed in E. coli and purifed by conventional chromatography, after refolding of the isolated inclusion bodies in a renaturation buffer.|
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