IL1a antibody (70-IR01)

Affinity purified Rabbit polyclonal IL1a antibody

Synonyms Polyclonal IL1a antibody, Anti-IL1a antibody, IL1a, IL-1a antibodyIL-1 alpha antibody, Interleukin 1 alphaantibody, ILa-1 antibody, ILa-1, ILa 1, ILa 1 antibody
Specificity Mouan IL-1a
Cross Reactivity To be determined by end-user
Applications ELISA, Inhibition, WB
Immunogen IL1a antibody was raised in rabbit using highly pure recombinant murine IL-1a as the immunogen.

Specifications

Host Rabbit
Molecular Weight 17.7 kDa (predicted detection band MW)
Form & Buffer Lyophilized from PBS, pH 7.2. Reconstitute in sterile water at a concentration of >0.2 mg/ml.

Usage & Assay Information

Usage Recommendations ELISA: 0.5-2 ug/ml, Inhibition: 0.03-0.05 ug/ml, WB: 0.1-0.2 ug/ml

Storage & Safety

Storage Store at -20 deg C until reconstitution. Following reconstitution product may be stored at 4 deg C in the short term. For long term storage aliquot and freeze at -20 deg C. Avoid repeated freeze/thaw cycles.

General Information

Biological Significance IL1a is a non-secreted proinflammatory cytokine produced in a variety of cells including monocytes, tissue macrophages, keratinocytes and other epithelial cells. Both IL1a and IL1beta binds to the same receptor and has similar if not identical biological properties. These cytokines have a broad range of activities including, stimulation of thymocyte proliferation, by inducing IL2 release, B-cell maturation and proliferation, mitogenic FGFlike activity and the ability to stimulate the release of prostaglandin and collagenase from synovial cells. However, whereas IL1beta is a secreted cytokine, IL1a is predominantly a cell-associated cytokine.

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Availability: In stock

Price: €225.80
Size: 50 ug
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