IL1b antibody (70R-13894)
Affinity purified Goat polyclonal IL1b antibody
Overview
Overview
| Synonyms | Polyclonal IL1b antibody, Anti-IL1b antibody, IL1b, ILb 1, ILb-1 antibody, IL-1b antibody, ILb 1 antibody, IL1 beta antibody, Interlekin 1 beta antibody, ILb-1 |
|---|---|
| Applications | WB |
| Immunogen | IL1b antibody was raised in Rabbit using a synthetic peptide corresponding to a sequence in the middle region of rat IL1B, different from the related Rabbit sequence by four amino acids, as the immunogen |
Images
Western Blot analysis using IL1b antibody (70R-13894)
Lane 1: Recombinant Mouse IL1beta Protein 10ng; Lane 2: Recombinant Mouse IL1beta Protein 5ng; Lane 3: Recombinant Mouse IL1beta Protein 2.5ng
Specifications
| Host | Rabbit |
|---|---|
| Isotype | IgG |
| Method of Purification | IL1b antibody was purified by affinity chromatography |
| Form & Buffer | Supplied in lyophilized form |
Usage & Assay Information
| Usage Recommendations | Optimal conditions to be determined by the end user |
|---|
Storage & Safety
| Storage | Store at 4 deg C for short term storage. For long term storage aliquot and store at -20 deg C, avoid repeated freeze/thaw cycles. |
|---|
General Information
| Biological Significance | IL1 is a name that designates two pleiotropic cytokines, IL1 alpha (IL1F1) and IL1Beta (IL1F2), which are the products of distinct genes. IL1 alpha and IL1Beta are structurally related polypeptides that share approximately 21% amino acid (aa) identity in human. Both proteins are produced by a wide variety of cells in response to inflammatory agents, infections, or microbial endotoxins. While IL1 alpha and IL1Beta are regulated independently, they bind to the same receptor and exert identical biological effects. IL1 RI binds directly to IL1 alpha or IL1Beta and then associates with IL1 R accessory protein (IL1 R3/IL1 R AcP) to form a highaffinity receptor complex that is competent for signal transduction. IL1 RII has high affinity for IL1Beta but functions as a decoy receptor and negative regulator of IL1Beta activity. |
|---|
Reviews
You need to be logged in to write a review. Please login here
Sorry there are currently no reviews for this product