IL1b protein (30R-2239)

Purified recombinant Human IL1b protein

Synonyms Interleukin-1 beta protein, ILb-1, IL1b protein, ILb 1, ILb-1 protein, IL1b, ILb 1 protein
Specificity Mouse
Species Human
Protein Type Recombinant
Applications FC
Assay Information A test is defined as the amount (ug) of antibody that will stain a cell sample in a final volume of 100 ul. Cell number should be determined empirically but can range from 105 to 108 cells/test.

Specifications

Expression System E.coli
Grade & Purity > 98% pure
Molecular Weight 18 kDa
Form & Buffer Supplied as a sterile liquid with phosphate buffered saline, pH7.2, 150 mM NaCl. 0.22 um filtered.
Concentration 5 ul (0.06 ug)/test

Usage & Assay Information

Usage Recommendations FC: 5 ul (0.06 ug)/test
Bioactivity The ED50 of this protein, as measured byD10S cell proliferation assay, is less than or equal to 125pg/ml. This corresponds to a specific activity of greater than or equal to 8 x 10e6 Units/mg.

Storage & Safety

Storage Store at -70 deg C or less.
Endotoxin Levels Less than 0.01 ng/ug cytokine as determined by the LAL assay.

General Information

Biological Significance Human IL-1beta, also called lymphocyte activating factor, endogenous pyrogen, leucocyte endogenous mediator, mononuclear cell factor, is produced by a wide variety of cells, including macrophages, dendritic cells, T cells and B cells. IL-1beta is mostly released and has only 20% amino acid homology with IL-1 alpha. The immune regulatory role of IL-1beta is exerted on a wide range of cells including lymphocytes, epithelial cells and fibroblasts. In vivo, it induces hypotension, fever, and acute phase response.

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Availability: In stock

Price: €1,505.11
Size: 100 ug
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