IL2 protein (Mouse) (30R-2156)
Purified recombinant Mouse IL2 protein
Overview
Overview
| Synonyms | IL 2 protein, Aldesleukin protein, IL-2 protein, Interleukin-2 protein, IL-2, T-cell growth factor protein, IL2, IL-2 protein, IL 2, TCGF protein, IL 2 protein, Interleukin 2 protein |
|---|---|
| Specificity | Rat |
| Species | Mouse |
| Protein Type | Recombinant |
| Applications | WB |
| Assay Information | It is recommended that the antibody be carefully titrated for optimal /formance in the assay of interest |
Specifications
| Expression System | E.coli |
|---|---|
| Grade & Purity | > 98% pure |
| Method of Purification | IL2 protein was purified by affinity chromatography. |
| Form & Buffer | Supplied as a sterile liquid with 10 mM sodium phosphate, pH 7.2, 150 mM NaCl, and 1.0% BSA. 0.22 um filtered. |
| Concentration | 500 ug/ml |
Usage & Assay Information
| Usage Recommendations | WB: = 2ug/ml |
|---|---|
| Bioactivity | Measured by mouse CTLL2 cell proliferation assay. The ED50 is 0.4 ng/ml, corresponding to a specific activity of 2.5 x 10^6 Units/mg. |
Storage & Safety
| Storage | Store at -70 deg C or less. |
|---|---|
| Endotoxin Levels | Less than 0.01 ng/ug cytokine as determined by the LAL assay. |
General Information
| Biological Significance | Mouse IL-2 is an ~17 kDa factor produced mainly by activated CD4+ T cells. IL-2 induces cell cycle progression of resting cells in an antigen non-specific manner and allows clonal expansion of activated T cells. IL-2 also acts on activated B cells, monocytes, NK cells, LAK cells, and on oligodendroglial cells in vitro. In addition, IL-2 plays a role in hematopoiesis, tumor surveillance and anti-inflammatory reactions, and hence is a central regulator of the immune response. Non-glycosylated IL-2 is biologically active. |
|---|
Reviews
You need to be logged in to write a review. Please login here
Sorry there are currently no reviews for this product