IL2 protein (Mouse) (30R-2156)

Purified recombinant Mouse IL2 protein

Synonyms IL 2 protein, Aldesleukin protein, IL-2 protein, Interleukin-2 protein, IL-2, T-cell growth factor protein, IL2, IL-2 protein, IL 2, TCGF protein, IL 2 protein, Interleukin 2 protein
Specificity Rat
Species Mouse
Protein Type Recombinant
Applications WB
Assay Information It is recommended that the antibody be carefully titrated for optimal /formance in the assay of interest

Specifications

Expression System E.coli
Grade & Purity > 98% pure
Method of Purification IL2 protein was purified by affinity chromatography.
Form & Buffer Supplied as a sterile liquid with 10 mM sodium phosphate, pH 7.2, 150 mM NaCl, and 1.0% BSA. 0.22 um filtered.
Concentration 500 ug/ml

Usage & Assay Information

Usage Recommendations WB: = 2ug/ml
Bioactivity Measured by mouse CTLL2 cell proliferation assay. The ED50 is 0.4 ng/ml, corresponding to a specific activity of 2.5 x 10^6 Units/mg.

Storage & Safety

Storage Store at -70 deg C or less.
Endotoxin Levels Less than 0.01 ng/ug cytokine as determined by the LAL assay.

General Information

Biological Significance Mouse IL-2 is an ~17 kDa factor produced mainly by activated CD4+ T cells. IL-2 induces cell cycle progression of resting cells in an antigen non-specific manner and allows clonal expansion of activated T cells. IL-2 also acts on activated B cells, monocytes, NK cells, LAK cells, and on oligodendroglial cells in vitro. In addition, IL-2 plays a role in hematopoiesis, tumor surveillance and anti-inflammatory reactions, and hence is a central regulator of the immune response. Non-glycosylated IL-2 is biologically active.

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Availability: In stock

Price: €298.57
Size: 20 ug
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