IL2 protein (Mouse) (30R-2241)

Purified recombinant Mouse IL2 protein

Synonyms IL 2 protein, Interleukin-2 protein, IL-2, Aldesleukin protein, Interleukin 2 protein, T-cell growth factor protein, IL 2 protein, IL2, IL-2 protein, IL-2 protein, TCGF protein, IL 2
Specificity Human
Species Mouse
Protein Type Recombinant
Applications FC
Assay Information This rat IgG1 isotype control has been used by flow cytometric analysis of mouse splenocyte suspension, This can be used at the same concentration as the experimental antibody.

Specifications

Expression System E.coli
Grade & Purity > 98% pure
Molecular Weight 18 kDa
Form & Buffer Supplied as a sterile liquid with 5 mM citric acid, 5 mMNaHPO4, 0.4 M NaCl, pH 4.0, 1 mM DTT. 0.22 um filtered.
Concentration 200 ug/ml

Usage & Assay Information

Bioactivity The ED50 of this protein, as measured by CTLL-2 cell proliferation assay, is less than or equal to 175pg/ml. This corresponds to a specific activity of greater than or equal to 5.7 x 10e6 Units/mg.

Storage & Safety

Storage Store at -70 deg C or less.
Endotoxin Levels Less than 0.01 ng/ug cytokine as determined by the LAL assay.

General Information

Biological Significance Mouse IL-2 is an ~17 kDa factor produced mainly by activated CD4+ T cells. IL-2 induces cell cycle progression of resting cells in an antigen non-specific manner and allows clonal expansion of activated T cells. IL-2 also acts on activated B cells, monocytes, NK cells, LAK cells, and on oligodendroglial cells in vitro. In addition, IL-2 plays a role in hematopoiesis, tumor surveillance and anti-inflammatory reactions, and hence is a central regulator of the immune response. Non-glycosylated IL-2 is biologically active.

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Availability: In stock

Price: €826.18
Size: 100 ug
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