IL2 protein (Mouse) (30R-AI021)
Purified recombinant Mouse IL2 protein
Overview
Overview
| Synonyms | IL-2 protein, IL 2 protein, IL-2, Interleukin 2 protein, IL-2 protein, IL2, IL 2 protein, Aldesleukin protein, T-cell growth factor protein, TCGF protein, IL 2, Interleukin-2 protein |
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| Species | Mouse |
| Protein Type | Recombinant |
| Applications | User optimized |
Specifications
| Residues | Region of IL2 protein corresponding to amino acids PTSSSTSSST AEAQQQQQQQ QQQQQHLEQL LMDLQELLSR MENYRNLKLP RMLTFKFYLP KQATELKDLQ CLEDELGPLR HVLDLTQSKS FQLEDAENFI SNIRVTVVKL KGSDNTFECQ FDDESATVVD FLRRWIAFCQ SIISTSPQ. |
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| Expression System | E.coli |
| Grade & Purity | > 98% pure |
| Molecular Weight | 17.2 kDa |
| Form & Buffer | Lyophilized from 10mM sodium citrate, pH 4.0. Reconstitute in water to a concentration of 0.1-1.0 mg/ml. Note: Slow to disolve. |
Usage & Assay Information
| Bioactivity | The ED50 as determined by the dose dependent stimulation of Mouse CTLL-2 cells is 5 x 10^6 units/mg. |
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Storage & Safety
| Storage | Store at 4 deg C until reconstitution. Following reconstitution aliquot and freeze at -20 deg C for long term storage. Avoid repeated freeze/thaw cycles. |
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| Endotoxin Levels | Endotoxin level is less than 0.1 ng per ug (1 EU/ug). |
General Information
| Biological Significance | IL2 is a powerful immunoregulatory lymphokine produced by T-cells in response to antigenic or mitogenic stimulation. IL2/IL2R signaling is required for T-cell proliferation and other fundamental functions which are essential for the immune response. IL2 stimulates growth and differentiation of B-cells, NK cells, lymphokine activated killer cells, monocytes, macrophages and oligodendrocytes. |
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