IL22 protein (30R-2661)
Purified recombinant Mouse IL22 protein
Overview
Overview
| Synonyms | TIFa protein, IL 22 protein, TIFIL-23 protein, IL-TIF protein, IL 22, MGC79384 protein, IL-22 protein, IL-D110 protein, IL-22 protein, ILTIF protein, IL-22, zcyto18 protein, MGC79382 protein, IL-10-related T-cell-derived-inducible factor protein, IL22 |
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| Species | Mouse |
| Protein Type | Recombinant |
Specifications
| Expression System | E.coli |
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| Grade & Purity | > 97% pure |
| Method of Purification | IL22 protein was purified using a a proprietary chromatographic technique. |
| Molecular Weight | 33.4 kDa |
| Form & Buffer | Supplied in lyophilized form from 1X PBS Solution |
Usage & Assay Information
| Bioactivity | The ED50 as determined by its ability to induce IL-10 secretion in Colo205 cells is less than 0.05 ng/ml, corresponding to a specific activity of 2 x 10^6 IU/mg |
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Storage & Safety
| Storage | Store at 4 deg C for short term storage. Aliquot and store at -20 deg C for long term storage. Avoid repeated freeze/thaw cycles. |
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| Endotoxin Levels | <0.1 ng/ug |
General Information
| Biological Significance | IL22 is a member of the IL10 family of regulatory cytokines which includes IL10, IL19, IL20, IL22, IL24 and IL26. Members of this family share partial homology in their amino acid sequences, but they are dissimilar in their biological functions. Produced by T lymphocytes, IL22 inhibits IL4 production by Th2 cells, and induces acute phase reactants in the liver and pancreas. IL22 signals through a receptor system consisting of IL10R- beta/CRF2-4 and IL22R, both of which are members of the class II cytokine-receptor family. |
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