IL22 protein (Mouse) (30R-AI141)

Purified recombinant Mouse IL22 protein

Synonyms Interleukin 22 protein, IL-22 protein, IL 22, IL-TIF protein, IL 22 protein, IL22, IL-22 protein, IL-22
Species Mouse
Protein Type Recombinant
Applications User optimized

Specifications

Residues Region of IL22 protein corresponding to amino acids MLPVNTRCKL EVSNFQQPYI VNRTFMLAKE ASLADNNTDV RLIGEKLFRG VSAKDQCYLM KQVLNFTLED VLLPQSDRFQ PYMQEVVPFL TKLSNQLSSC HISGDDQNIQ KNVRRLKETV KKLGESGEIK AIGELDLLFM SLRNACV.
Expression System E.coli
Grade & Purity > 98% pure
Molecular Weight 33.4 kDa
Form & Buffer Supplied as a lyophilized powder.

Usage & Assay Information

Bioactivity Determined by its ability to induce STAT3 activation in COLO 205 cells. The expected ED50 for this effect is 150-400 pg/ml.

Storage & Safety

Storage Store at 4 deg C until reconstitution. Following reconstitution aliquot and freeze at -20 deg C for long term storage. Avoid repeated freeze/thaw cycles.
Endotoxin Levels Endotoxin level is less than 0.1 ng per ug (1 EU/ug).

General Information

Biological Significance IL22 is a member of the IL10 family of regulatory cytokines which includes IL10, IL19, IL20, IL22, IL24 and IL26. Members of this family share partial homology in their amino acid sequences, but they are dissimilar in their biological functions. Produced by T lymphocytes, IL22 inhibits IL4 production by Th2 cells, and induces acute phase reactants in the liver and pancreas. IL22 signals through a receptor system consisting of IL10R-beta/CRF2-4 and IL22R, both of which are members of the class II cytokine-receptor family.

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Availability: In stock

Price: €225.77
Size: 10 ug
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