IL2RG protein (80R-4207)
Recombinant Human IL2RG protein with His tag
Overview
Overview
| Synonyms | Human IL2RG protein, Recombinant IL2RG protein, Cytokine receptor common subunit gamma protein, CD132 protein, CIDX protein, IL-2RG protein, IMD4 protein, P64 protein, SCIDX protein, SCIDX1 protein |
|---|---|
| Species | Human |
| Protein Type | Recombinant |
| Applications | Control, SDS-PAGE |
Images
Coomassie blue stained SDS-PAGE showing analysis of IL2RG protein(80R-4207)
Figure annotation denotes ug of protein loaded and % gel used.
Specifications
| Residues | 23-262 amino acids of Human IL2RG protein: LNTTILTPNG NEDTTADFFL TTMPTDSLSV STLPLPEVQC FVFNVEYMNC TWNSSSEPQP TNLTLHYWYK NSDNDKVQKC SHYLFSEEIT SGCQLQKKEI HLYQTFVVQL QDPREPRRQA TQMLKLQNLV IPWAPENLTL HKLSESQLEL NWNNRFLNHC LEHLVQYRTD WDHSWTEQSV DYRHKFSLPS VDGQKRYTFR VRSRFNPLCG SAQHWSEWSH PIHWGSNTSK ENPFLFALEA HHHHHH |
|---|---|
| Expression System | Insect cells |
| Grade & Purity | > 80% pure |
| Molecular Weight | 29.0 kDa |
| Tag/Conjugate | His tag |
| Form & Buffer | Supplied as liquid in PBS (pH 7.4) |
| Concentration | 500 ug/ml |
Storage & Safety
| Storage | Store at 4 deg C for short term. For long term storage, aliquot and store at -20 deg C. Avoid repeated freeze thaw cycles. |
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| Endotoxin Levels | LAL method determined levels of < 1.0 EU/ug of protein |
General Information
| Biological Significance | IL2RG, also known as Interleukin-2 receptor common subunit gamma, is a cytokine receptor sub-unit that is common to the receptor complexes for at least six different interleukin receptors. This protein is located on the surface of immature blood-forming cells in bone marrow. One end of the protein resides outside of the cell where it binds to cytokines and the other end of the protein resides in the interior of the cell where it transmits signals to the cell's nucleus. The common gamma chain partners with other proteins to direct blood-forming cells to form lymphocytes. It also directs the growth and maturation of lymphocyte subtypes. These cells kill viruses, make antibodies, and help regulate the entire immune system. Recombinant human IL2RG, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques. |
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