IL3 protein (30R-AI023)

Purified recombinant Human IL3 protein

Synonyms IL-3 protein, Multi-CSF protein, Interleukin 3 protein, HCGF protein, IL-3, IL 3, IL-3 protein, IL 3 protein, Mast cell growth factor protein, MCGF protein, P-cell stimulation factor protein, IL3
Species Human
Protein Type Recombinant
Applications User optimized

Specifications

Residues Region of IL3 protein corresponding to amino acids APMTQTTSLK TSWVNCSNMI DEIITHLKQP PLPLLDFNNL NGEDQDILME NNLRRPNLEA FNRAVKSLQN ASAIESILKN LLPCLPLATA APTRHPIHIK DGDWNEFRRK LTFYLKTLEN AQAQQTTLSL AIF.
Expression System E.coli
Grade & Purity > 98% pure
Molecular Weight 15 kDa
Form & Buffer Supplied lyophilized with no additives. Reconstitute in water to a concentration of 0.1 - 1.0 mg/ml.

Usage & Assay Information

Bioactivity The ED50 as determined by the dose-dependent stimulation of the proliferation of human TF-1 cells is approximately 0.1 ng/ml, corresponding to a specific activity of approximately 1 x 10^7 units/mg.

Storage & Safety

Storage Store at 4 deg C until reconstitution. Following reconstitution aliquot and freeze at -20 deg C for long term storage. Avoid repeated freeze/thaw cycles.
Endotoxin Levels Endotoxin level is less than 0.1 ng per ug (1 EU/ug).

General Information

Biological Significance IL3 is a hematopoietic growth factor that promotes the survival, differentiation and proliferation of committed progenitor cells of the megakaryocyte, granulocyte-macrophage, erythroid, eosinophil, basophil and mast cell lineages. Produced by T cells, mast cells and eosinophils, IL3 enhances thrombopoieses, phagocytosis, and antibody-mediated cellular cytotoxicity. Its ability to activate monocytes suggests that IL3 may have additional immunoregulatory roles. Many of the IL3 activities depend upon co-stimulation with other cytokines.

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Availability: In stock

Price: €211.69
Size: 10 ug
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