IL32 protein (His tag) (80R-1113)

Purified recombinant Human IL32 protein

Synonyms Natural killer cells protein 4 protein, Interleukin 32 isoform A IL 32alpha protein, TAIFd protein, IL-32 protein, IL 32 protein, IL 32gamma protein, TAIFc protein, IL 32delta protein, IL 32beta protein, Tumor necrosis factor alpha-inducing factor (TAIF) protein, Interleukin 32 isoform A protein, TAIFa protein, IL32, Interleukin 32 protein, IL-32 protein, IL-32, IL 32, NK4 protein, TAIFb protein, TAIF protein, Interleukin 32 protein, il32, NK 4 protein, Natural killer cells protein 4(NK4) protein
Species Human
Protein Type Recombinant
Applications SDS-PAGE

Specifications

Residues 1-131 amino acids: MRGSHHHHHH GMASMTGGQQ MGRDLYDDDD KDRWGSHMCF PKVLSDDMKK LKARMHQAIE RFYDKMQNAE SGRGQVMSSL AELEDDFKEG YLETVAAYYE EQHPELTPLL EKERDGLRCR GNRSPVPDVE DPATEEPGES FCDKSYGAPR GDKEELTPQK CSEPQSSK
Expression System E.coli
Grade & Purity > 95% pure
Molecular Weight 19.1 kDa (168aa), confirmed by MALDI-TOF.
Tag/Conjugate His tag
Form & Buffer Supplied as a liquid in 20mM Tris-HCl buffer, pH 8.0, containing 1mM DTT, and 10% glycerol.
Concentration 1 mg/ml

Storage & Safety

Storage Store at 4 deg C for short term storage (1/2 weeks). Aliquot and store at -20 deg C or - 70 deg C for long term storage. Avoid repeated freeze/thaw cycles.

General Information

Biological Significance Interleukin 32 isoform A belongs to cytokine family. This protein expression is increased after the activation of T-cells by mitogens or the activation of NK cells by IL-2. It has the ability to induce proinflammatory cytokines such as TNFalpha and IL8 in THP1 cells, and activates typical cytokine signaling pathways involving NFkB and p38. IL-32 can also support osteoclast differentiation but not osteoclast activation by regulating the MAPK/ERK pathway and the actin cytoskeleton. Recombinant human Interleukin 32, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography.

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Availability: In stock

Price: €277.55
Size: 100 ug
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