IL33 protein (His tag) (80R-3995)

Recombinant Mouse IL33 protein

Synonyms Recombinant IL33 protein Interleukin-33 protein, 230117N10Rik protein, IL-33 protein, Il-33 protein, Il1f11 protein, Interleukin 33 protein
Species Mouse
Protein Type Recombinant
Applications SDS-PAGE

Images

Coomassie blue stained SDS-PAGE showing analysis of IL33 protein (His tag) (80R-3995)

Figure annotation denotes ug of protein loaded and % gel used.

Specifications

Residues 109-266 aa; MGSSHHHHHH SSGLVPRGSH MGSSIQGTSL LTQSPASLST YNDQSVSFVL ENGCYVINVD DSGKDQEQDQ VLLRYYESPC PASQSGDGVD GKKLMVNMSP IKDTDIWLHA NDKDYSVELQ RGDVSPPEQA FFVLHKKSSD FVSFECKNLP GTYIGVKDNQ LALVEEKDES CNNIMFKLSK I
Expression System E.coli
Grade & Purity > 85% pure
Molecular Weight 18.1 kDa
Tag/Conjugate His tag
Form & Buffer Supplied as liquid in PBS,10% glycerol, 1 mM DTT
Concentration 500 ug/ml

Storage & Safety

Storage Store at 4 deg C for 1-2 weeks. For long term storage, aliquot and store at -20 to -70 deg C. Avoid repeated freeze/thaw cycles.

General Information

Biological Significance Interleukin 33 (IL-33) is a 32kDa proinflammatory cytokine that may also regulate gene transcription in producer cells. IL-33 is structurally related to IL-1, which induces helper T cells to produce type 2 cytokines and acts through the receptor IL1RL-1 (IL1 receptor-like-1), which is known also as ST2. Binding of IL-33 to this receptor activates NF-kappa-B and MAP kinases and induces in vitro Th2 cells to produce cytokines. In vivo, IL-33 induces expression of IL-4, IL-5, IL-13 and leads to severe pathological changes in mucosal organs and in vitro, it can be divided to N-terminal fragment of 12kDa and C-terminal fragment of 18kDa by cleavage of caspase-1. Recombinant mouse IL33 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.

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Images

  • 

Coomassie blue stained SDS-PAGE showing analysis of IL33 protein (His tag) (80R-3995)



 | 

Figure annotation denotes ug of protein loaded and % gel used.

Availability: In stock

Price: €306.75
Size: 50 ug
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