IL34 protein (His tag) (80R-4085)
Recombinant Mouse IL34 protein (His tag)
Overview
Overview
| Synonyms | Interleukin-34 protein, protein |
|---|---|
| Species | Mouse |
| Protein Type | Recombinant |
| Applications | SDS-PAGE |
Images
SDS-PAGE analysis of IL34 protein (His tag) (80R-4085)
Figure annotated with amount of protein analysed and % SDS PAGE gel.
Specifications
| Residues | 21-235 amino acids: MGSSHHHHHH SSGLVPRGSH MNENLEIWTL TQDKECDLTG YLRGKLQYKN RLQYMKHYFP INYRIAVPYE GVLRVANITR LQKAHVSERE LRYLWVLVSL NATESVMDVL LEGHPSWKYL QEVQTLLENV QRSLMDVEIG PHVEAVLSLL STPGLSLKLV RPKALLDNCF RVMELLYCSC CKQSPILKWQ DCELPRLHPH SPGSLMQCTA TNVYPLSRQT PTSLPGSPSS SHGSLP |
|---|---|
| Expression System | E.coli |
| Grade & Purity | > 85% pure |
| Molecular Weight | 26.8 kDa |
| Tag/Conjugate | His tag |
| Form & Buffer | Supplied as liquid in 20mM Tris-HCl buffer, pH 8.0 containing 10% Glycerol |
| Concentration | 500 ug/ml |
Storage & Safety
| Storage | Store at 4 deg C short term. Aliquot and store at -70 deg C for long term and avoid repeated freeze thaw cycles |
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General Information
| Biological Significance | IL34 is a cytokine that promotes the proliferation, survival and differentiation of monocytes and macrophages. This protein promotes the release of proinflammatory chemokines, and thereby plays an important role in innate immunity and in inflammatory processes. It plays an important role in the regulation of osteoclast proliferation and differentiation, and in the regulation of bone resorption. Signaling via CSF1R and its downstream effectors stimulates phosphorylation of MAPK1/ERK2 AND MAPK3/ERK1. Recombinant Mouse IL34 protein, fused to His-tag at N-terminus, was expressed in E.coli. |
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