IL4 antibody (allophycocyanin) (61R-1791)

Rat monoclonal IL4 antibody (allophycocyanin)

Synonyms Monoclonal IL4 antibody, Anti-IL4 antibody, IL4, IL 4, B-cell stimulatory factor 1 antibody, B-cell IgG differentiation factor antibody, IL-4 antibody, Lymphocyte stimulatory factor 1 antibody, IL-4 antibody, IGG1 induction factor antibody, B-cell growth factor 1 antibody, IL4 antibody (APC), IL4 antibody, IL-4, BSF-1 antibody, IL 4 antibody, Interleukin-4 antibody
Applications FC
Assay Information A test is defined as the amount (ug) of antibody that will stain a cell sample in a final volume of 100 ul. Cell number should be determined empirically but can range from 105 to 108 cells/test. It is recommended that the antibody be carefully titrated for optimal performance in the assay of interest.

Specifications

Host Rat
Clone 11B11
Isotype IgG1 kappa
Tag/Conjugate Allophycocyanin
Form & Buffer Supplied in aqueous buffer with 0.09% sodium azide, may contain carrier protein/stabilizer.
Concentration 200 ug/ml

Usage & Assay Information

Usage Recommendations FC: = 0.06 ug/test

Storage & Safety

Storage Store at 2-8 deg C. Do not freeze. Protect from light.

General Information

Biological Significance The 11B11 antibody reacts with mouse interleukin-4, a 14 kD cytokine. The 11B11 antibody is a neutralizing antibody. Mouse IL-4, also known as BCDF, BCGF-1 and BSF-1, is secreted by activated Th2 and natural killer T cells, and to a lesser extent by Th1 and mast cells. IL-4 is species-specific and promotes proliferation and differentiation of B cells. IL-4, in conjunction with other signals such as CD40, induces Ig isotype switching of B cells and the upregulation of surface MHC class II and CD23.

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