IL5 protein (30R-2490)
Purified recombinant Mouse IL5 protein
Overview
Overview
| Synonyms | IL-5, IL-5 protein, IL5, TRF protein, IL-5 protein, IL 5, T-cell replacing factor protein, IL-5 protein, Interleukin 5 protein, BCGF-II protein, B-cell growth factor II protein, IL-5 protein, Eosinophil differentiation factor protein, IL 5 protein, IL 5 protein, Cytotoxic T-lymphocyte inducer protein, Interleukin-5 protein |
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| Species | Mouse |
| Protein Type | Recombinant |
Specifications
| Expression System | E.coli |
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| Grade & Purity | > 97% pure |
| Method of Purification | IL5 protein was purified using a a proprietary chromatographic technique. |
| Molecular Weight | 26.2 kDa |
| Form & Buffer | Supplied in lyophilized form from 20 mM Sodium phosphate buffer, pH 7.5 |
Usage & Assay Information
| Bioactivity | The ED50, as calculated by the dose-dependent induction of TF-1 cell proliferation, is 17 ng/ml |
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Storage & Safety
| Storage | Store at 4 deg C for short term storage. Aliquot and store at -20 deg C for long term storage. Avoid repeated freeze/thaw cycles. |
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| Endotoxin Levels | <0.1 ng/ug |
General Information
| Biological Significance | Interleukin-5 is a glycoprotein also known as EDF and TRF. It is involved in B-cell growth and eosinophil activation. IL-5 has been shown to be expressed in Th2, mast cells and eosinophils and is regulated by GATA-3, in addition to other transcription factors. IL-5 signals its biological effect through interaction with the IL-5 receptor. |
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