IL6 antibody (10R-I164A)
Mouse monoclonal IL6 antibody
Overview
Overview
| Synonyms | Monoclonal IL6 antibody, Anti-IL6 antibody, BCDF antibody, IL-6 antibody, IL-6, B cell differentiation factor antibody, IFN-beta2 antibody, IL 6 antibody, HPGF antibody, IL 6, HSF antibody, IL6, MGI-2 antibody, Interleukin 6 antibody, BSF-2 antibody, 26 kDa antibody antibody, IL-6 antibody |
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| Specificity | Human IL-6 |
| Cross Reactivity | To be determined by end-user |
| Applications | ELISA, Inhibition, WB |
| Immunogen | IL6 antibody was raised in mouse using recombinant human IL-6 as the immunogen. |
Specifications
| Host | Mouse |
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| Clone | M912273 |
| Isotype | IgG1 kappa |
| Molecular Weight | 21.7 kDa (predicted detection band MW) |
| Form & Buffer | Lyophilized from PBS. Reconstitute in sterile water to a concentration of 1.0 mg/ml |
Usage & Assay Information
| Usage Recommendations | ELISA: 4-8 ug/ml, ib: 0.2-0.4 ug/ml |
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Storage & Safety
| Storage | Store at -20 deg C until reconstitution. Following reconstitution product may be stored at 4 deg C in the short term. For long term storage aliquot and freeze at -20 deg C. Avoid repeated freeze/thaw cycles. |
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General Information
| Biological Significance | IL6 is a pleiotropic cytokine that plays an important role in host defense by regulating immune and inflammatory responses. Produced by T cells, monocytes, fibroblasts, endothelial cells and keratinocytes, IL6 has diverse biological functions. It stimulates B-cell differentiation and antibody production, synergizes with IL3 in megakaryocyte development and platelet production, induces expression of hepatic acute-phase proteins, and regulates bone metabolism. IL6 signals through the IL6 receptor system that consists of two chains, IL6R alpha and gp130. Mouse IL6 is inactive on human cells, while both human and Mouse are equally active on Mouse cells. |
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