IL6 antibody (70R-13895)
Affinity purified Rabbit polyclonal IL6 antibody
Overview
Overview
| Synonyms | Polyclonal IL6 antibody, Anti-IL6 antibody, B cell differentiation factor antibody, IL6, IL-6 antibody, IL 6 antibody, Interleukin 6 antibody, IL-6 antibody, HPGF antibody, MGI-2 antibody, 26 kDa antibody antibody, HSF antibody, IFN-beta2 antibody, IL-6, IL 6, BSF-2 antibody, BCDF antibody |
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| Applications | WB |
| Immunogen | IL6 antibody was raised in Rabbit using a synthetic peptide corresponding to a sequence at the C-terminal of rat IL6, different from the related Rabbit sequence by two amino acids, as the immunogen |
Images
Specifications
| Host | Rabbit |
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| Isotype | IgG |
| Method of Purification | IL6 antibody was purified by affinity chromatography |
| Form & Buffer | Supplied in lyophilized form |
Usage & Assay Information
| Usage Recommendations | Optimal conditions to be determined by the end user |
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Storage & Safety
| Storage | Store at 4 deg C for short term storage. For long term storage aliquot and store at -20 deg C, avoid repeated freeze/thaw cycles. |
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General Information
| Biological Significance | IL6 is a pleiotropic cytokine that plays an important role in host defense by regulating immune and inflammatory responses. Produced by T cells, monocytes, fibroblasts, endothelial cells and keratinocytes, IL6 has diverse biological functions. It stimulates B-cell differentiation and antibody production, synergizes with IL3 in megakaryocyte development and platelet production, induces expression of hepatic acute-phase proteins, and regulates bone metabolism. IL6 signals through the IL6 receptor system that consists of two chains, IL6R alpha and gp130. Mouse IL6 is inactive on human cells, while both human and Mouse are equally active on Mouse cells. |
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