IL9 protein (Mouse) (30R-AI147)
Purified recombinant Mouse IL9 protein
Overview
Overview
| Synonyms | p40 cytokine protein, IL-9 protein, IL-9, IL 9, T-cell growth factor p40 protein, IL9, Interleukin 9 protein, IL 9 protein, IL-9 protein |
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| Species | Mouse |
| Protein Type | Recombinant |
| Applications | User optimized |
Specifications
| Residues | Region of IL9 protein corresponding to amino acids MQRCSTTWGI RDTNYLIENL KDDPPSKCSC SGNVTSCLCL SVPTDDCTTP CYREGLLQLT NATQKSRLLP VFHRVKRIVE VLKNITCPSF SCEKPCNQTM AGNTMSFLKS LLGTFQKTEM QRQKSRP. |
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| Expression System | E.coli |
| Grade & Purity | > 98% pure |
| Molecular Weight | 14.3 kDa |
| Form & Buffer | Supplied as a lyophilized powder. |
Usage & Assay Information
| Bioactivity | The ED50 as determined by the dose-dependent proliferation of human MO7e cells is 2 x 10^6 units/mg. |
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Storage & Safety
| Storage | Store at 4 deg C until reconstitution. Following reconstitution aliquot and freeze at -20 deg C for long term storage. Avoid repeated freeze/thaw cycles. |
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| Endotoxin Levels | Endotoxin level is less than 0.1 ng per ug (1 EU/ug). |
General Information
| Biological Significance | IL9 is an immunoregulatory cytokine produced by IL2 activated Th2 lymphocytes. IL9 enhances the proliferation of T lymphocytes, mast cells, erthroid precursor cells and megakaryoblastic leukemia cell lines. Over-expression of IL9 has been implicated in the pathogenesis of anaplastic lymphoma and Hodgkin's disease. Whereas Mouse IL9 can function on human cells, human IL9 is inactive on mouse cells. |
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