Inhibin beta A antibody (70R-13185)

Affinity purified Rabbit polyclonal Inhibin beta A antibody

Synonyms Polyclonal Inhibin beta A antibody, Anti-Inhibin beta A antibody, FSH-releasing protein antibody, follicle-stimulating hormone-releasing protein antibody, erythroid differentiation factor antibody, inhibin beta A (activin A activin AB alpha polypeptide) antibody, INHBA antibody, FRP antibody, inhibin beta A chain antibody, EDF antibody, activin beta-A chain antibody
Cross Reactivity Human
Applications ICC, IF, IHC-P, WB

Images

Immunofluorescent staining using Inhibin beta A antibody (70R-13185)

Immunofluorescence analysis of paraformaldehyde-fixed HeLa, using Inhibin beta-A antibody at 1:200 dilution.

Specifications

Host Rabbit
Isotype IgG
Method of Purification Inhibin beta A antibody was purified by antigen-affinity chromatography
Molecular Weight 47 kDa
Form & Buffer Supplied as a concentrated soloution containing 0.1M Tris, 0.1M Glycine, 10% Glycerol (pH 7.0). 0.01% Thimerosal was added as a preservative.
Concentration 1 mg/ml

Usage & Assay Information

Usage Recommendations IF:1:100-1:500, ICC:1:100-1:500, IHC-P: 1:100-1:500, WB: 1:500-1:3000

Storage & Safety

Storage Store at 4 deg C for short term storage. Aliquot and store at -20 deg C for long term storage. Avoid repeated freeze/thaw cycles.

General Information

Biological Significance The inhibin beta A subunit joins the alpha subunit to form a pituitary FSH secretion inhibitor. Inhibin has been shown to regulate gonadal stromal cell proliferation negatively and to have tumor-suppressor activity. In addition, serum levels of inhibin have been shown to reflect the size of granulosa-cell tumors and can therefore be used as a marker for primary as well as recurrent disease. Because expression in gonadal and various extragonadal tissues may vary severalfold in a tissue-specific fashion, it is proposed that inhibin may be both a growth/differentiation factor and a hormone. Furthermore, the beta A subunit forms a homodimer, activin A, and also joins with a beta B subunit to form a heterodimer, activin AB, both of which stimulate FSH secretion. Finally, it has been shown that the beta A subunit mRNA is identical to the erythroid differentiation factor subunit mRNA and that only one gene for this mRNA exists in the human genome.

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Images

  • <div><font face=Calibri size=2>Immunofluorescent staining using Inhibin beta A antibody (70R-13185)</font></div>     | Immunofluorescence analysis of paraformaldehyde-fixed HeLa, using Inhibin beta-A antibody at 1:200 dilution.
  • <div><font face=Calibri size=2>Immunohistochemical staining using Inhibin beta A antibody (70R-13185)</font></div>     | Immunohistochemical staining of paraffin-embedded CLEAR CELL OVCA xenograft using Inhibin beta A antibody at a dilution of 1:500
  • <div><font face=Calibri size=2>Western blot analysis using Inhibin beta A antibody (70R-13185)</font></div>     | Western blot analysis of 30 ug whole cell lysate (A:H1299; B:HeLa S3; C:Hep G2) using a 10 % SDS PAGE gel and Inhibin beta A antibody at a dilution of 1:1000

Availability: In stock

Price: €323.11
Size: 100 ul
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