Insulin R alpha antibody (70R-13801)

Affinity purified Rabbit polyclonal Insulin R alpha antibody

Synonyms Polyclonal Insulin R alpha antibody, Anti-Insulin R alpha antibody, Insulin Receptor alpha antibody
Applications IHC-P, WB
Immunogen Insulin R alpha antibody was raised in Rabbit using a synthetic peptide corresponding to a sequence at the N-terminal of human Insulin R alpha, identical to the related rat and Rabbit sequence as the immunogen

Images

Immunohistochemical staining using Insulin R alpha antibody (70R-13801)

Immunohistochemistry of paraffin-embedded section of Rat Cardiac Muscle Tissue

Specifications

Host Rabbit
Isotype IgG
Method of Purification Insulin R alpha antibody was purified by affinity chromatography
Form & Buffer Supplied in lyophilized form

Usage & Assay Information

Usage Recommendations Optimal conditions to be determined by the end user

Storage & Safety

Storage Store at 4 deg C for short term storage. For long term storage aliquot and store at -20 deg C, avoid repeated freeze/thaw cycles.

General Information

Biological Significance Insulin receptor is a tetramer of 2 alpha and 2 beta subunits. The alpha and beta subunits are coded by a single gene and are joined by disulfide bonds, a mechanism parallel to that of its ligand, insulin. The insulin receptor has an intrinsic tyrosine kinase activity that is essential for signal transduction. A mutant insulin receptor gene lacking almost the entire kinase domain has been identified in an individual with type A insulin resistance and acanthosis nigricans.

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Images

  • <div><font face=Calibri size=2>Immunohistochemical staining using Insulin R alpha antibody (70R-13801)</font></div>     | Immunohistochemistry of paraffin-embedded section of Rat Cardiac Muscle Tissue
  • <div><font face=Calibri size=2>Western Blot analysis using Insulin R alpha antibody (70R-13801)</font></div>     | Lane 1: MCF-7 Cell Lysate; Lane 2: Hela Cell Lysate; Lane 3: Jurkat Cell Lysate

Availability: In stock

Price: €220.86
Size: 100 ug
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