IP10 protein (30R-2227)

Purified recombinant Human IP10 protein

Synonyms IP 10, IP-10, IP10, IP 10 protein, IP-10 protein, IP10 protein
Specificity Mouse
Species Human
Protein Type Recombinant
Applications User optimized
Assay Information Currently there is no reliable bioassay available for recombinant mouse IL-17B.

Specifications

Expression System E.coli
Grade & Purity > 97% pure
Method of Purification IP10 protein was purified by affinity chromatography.
Molecular Weight 8.8 kDa
Form & Buffer Supplied as a sterile liquid with phosphate buffered saline, 1 % BSA, pH 7.2

Usage & Assay Information

Bioactivity The bioactivity of this protein was determined by transmigration assay of human T lymphocytes, with maximum chemotaxis observed at 100-200 ng/ml.

Storage & Safety

Storage Store at -70 deg C or less.
Endotoxin Levels Less than 0.01 ng/ug cytokine as determined by the LAL assay.

General Information

Biological Significance IP-10, or Interferon Gamma Inducible Protein 10, is a CXC chemokine also known as CXCL10. IP-10 is induced in monocytes, fibroblasts, and endothelial cells by IFNgamma. It is also induced by LPS, IL-1beta, TNF- alpha, IL-12, and viral infection. IP-10 is a chemoattractant for CXCR3+ T cells, which plays an important role in Th1-type inflammatory diseases, as well as several endocrine-related autoimmune diseases such as Hashimoto's thyroiditis. Recombinant human IP-10 produced in E.Coli is a single, non-glycosylated polypeptide containing 77 amino acids and with a molecular mass of 8.5 kDa.

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Availability: In stock

Price: €226.58

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Price: €226.58
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