Isocitrate Dehydrogenase protein (Porcine) (30-1140)

Purified native Porcine Isocitrate Dehydrogenase protein

Specifications

Source Porcine Heart
Form & Buffer Supplied in Lyophilized form

Usage & Assay Information

Bioactivity > 35 units/mg protein

Storage & Safety

Storage Store at 2-8 deg C for short term storage. For long term storage aliquot and store at -20 deg C

General Information

Biological Significance Isocitrate dehydrogenase also known as IDH, is an enzyme that participates in the citric acid cycle. It catalyzes the third step of the cycle: the oxidative decarboxylation of isocitrate, producing alpha-ketoglutarate (alpha-ketoglutarate) and CO2 while converting NAD+ to NADH. This is a two-step process, which involves oxidation of isocitrate (a secondary alcohol) to oxalosuccinate (a ketone), followed by the decarboxylation of the carboxyl group beta to the ketone, forming alpha-ketoglutarate. Another isoform of the enzyme catalyzes the same reaction, however this reaction is unrelated to the citric acid cycle, is carried out in the cytosol as well as the mitochondrion and peroxisome and uses NADP+ as a cofactor instead of NAD+.

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Availability: In stock

Price: €69.53
Size: 100 units
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