JEV NS1 protein (80-1544)
Purified Recombinant JEV NS1 protein (His tag)
Overview
Overview
| Synonyms | JEV NS1 antigen, Japanese encephalitis virus NS1 glycoprotein, Japanese encephalitis virus NS1 protein, NS1 protein, Japanese encephalitis virus protein |
|---|---|
| Species | Viral |
| Protein Type | Recombinant |
Specifications
| Expression System | 293 cells |
|---|---|
| Grade & Purity | > 95% pure |
| Tag/Conjugate | His tag |
| Form & Buffer | Supplied in DPBS, pH 7.4 |
| Concentration | 500 ug/ml |
Storage & Safety
| Storage | Store at -80 deg C |
|---|
General Information
| Product Use | JEV NS1 protein for use in the research laboratory |
|---|---|
| Biological Significance | The Japanese encephalitis viral genome encodes 7 non-structural proteins NS1-NS5. NS1 contains N-linked carbohydrate chains at positions 130 and 207. It is not incorporated into the virion but exists in the host cell, on the cell surface and can also be extracellular. |
| Implications in Disease | Less than 1% of people infected with Japanese encephalitis (JE) virus develop clinical illness. In persons who develop symptoms, the incubation period (time from infection until illness) is typically 5-15 days. Initial symptoms often include fever, headache, and vomiting. Mental status changes, neurologic symptoms, weakness, and movement disorders might develop over the next few days. Seizures are common, especially among children. No specific treatments have been found to benefit patients with JE, but hospitalization for supportive care and close observation is generally required. |
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