JNK1 antibody (20R-2901)
Rabbit polyclonal JNK1 antibody
Overview
Overview
| Synonyms | Polyclonal JNK1 antibody, Anti-JNK1 antibody, MAPK8 antibody, mitogen-activated protein kinase 8 antibody, BOS_24299 antibody, c-jun NH2-terminal kinase antibody, c-Jun N-terminal kinase 1 antibody, janus kinase 1 antibody, JNK antibody, jnk1 antibody, JNK1A2 antibody, JNK1 beta1 protein kinase antibody, JNK21B1/2 antibody, JNK-46 antibody, JUN N-terminal kinase antibody, MAPK 8 antibody, MAP kinase 8 antibody, mitogen activated protein kinase 8 antibody, mitogen-activated protein kinase 8 isoform JNK1 alpha1 antibody, mitogen-activated protein kinase 8 isoform JNK1 beta2 antibody, p54 gamma antibody, PANDA_014394 antibody, PRKM8 antibody, protein kinase mitogen-activated 8 antibody, sapk1 antibody, SAPK1c antibody, SAPK gamma antibody, stress-activated protein kinase 1 antibody, stress-activated protein kinase 1c antibody, stress-activated protein kinase JNK1 antibody |
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| Cross Reactivity | Human, Mouse, Rat |
| Applications | WB |
| Immunogen | JNK1 antibody was raised in Rabbit using a synthetic target peptide as the immunogen |
Specifications
| Host | Rabbit |
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| Isotype | IgG |
| Method of Purification | JNK1 antibody was purified by Protein A affinity chromatography |
| Form & Buffer | Supplied in liquid form in HEPES buffer with 0.15M NaCl, 0.01% BSA, 0.03% sodium azide, and 50% glycerol |
Usage & Assay Information
| Usage Recommendations | WB: 1:1000-2000 |
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Storage & Safety
| Storage | Aliquot and store for 1 year at -20 deg C, avoid freeze/thaw cycles |
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General Information
| Biological Significance | The c-Jun N-terminal protein kinases (JNKs) are a family of serine/threonine protein kinases of the mitogen-activated protein kinase (MAPK) group. JNKs, which are essential regulators of physiological and pathological processes, are involved in several diseases including diabetes, atherosclerosis, stroke, and Parkinson's and Alzheimer's diseases. The JNK family consists of three isoforms; JNK1 and JNK2, which are ubiquitous, and JNK3, which is present primarily in the heart, brain and testis. Differential splicing and exon use yield 10 isoforms of JNK. JNK1 is an important mediator of insulin resistance associated with obesity, but it is also indispensable for the intact cytoarchitecture of the brain. |
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